What is the significance of a negative fetal fibronectin (fFN) test result?

A negative fetal fibronectin (fFN) test result holds significant clinical importance, particularly in the context of predicting preterm labor. When the fFN test is negative, it indicates a very low likelihood of delivery occurring within the next 7 to 14 days. This finding provides reassurance that the risk of preterm delivery is minimal, allowing healthcare providers to focus on managing patients without immediate interventions for potential early labor.

The fFN test assesses the presence of fetal fibronectin in vaginal secretions, which acts as a glue-like protein that binds the fetal membranes to the uterine lining. A negative result suggests that there is sufficient time before delivery, enabling monitoring and possibly delaying interventions until closer to term. It is important to note that a negative result does not completely rule out the risk of preterm birth later on; however, it helps in making informed decisions about patient care in the short term.